Effective Mesothelioma Treatment: Lovastatin
Lovastatin, a well-tolerated drug commonly used to treat high cholesterol, has shown positive 
results as an adjunctive, or secondary, drug treatment to inhibit mesothelial cell growth.
Early studies on Lovastatin originally excited researchers because of the unexpected, yet potent side effect it had on killing cancer cells. However, it was soon noted that humans were not able to tolerate the high doses of the drug needed to produce the anti-cancer effect, and plans to use the drug in cancer trials were temporarily postponed.
Researchers are now reconsidering Lovastatin and its potential uses in cancer treatment. One Nashville, Tennessee clinician has already been using the drug to treat some of the most serious cancers, including pleural mesothelioma.
NeoPlas Innovation Director of Research, Dr. Stephen Cantrell, says the key is using interferon combined with Lovastatin to reduce the toxicity of the cholesterol drug. The treatment protocol includes administration of a very precisely timed series of low-dose interferon and Lovastatin.
Another advantage of using Lovastatin is the absence of toxic side-effects usually associated with standard chemotherapy. The most prevalent side-effect with Lovastatin treatment is fatigue, unlike other chemotherapy drugs that can cause nausea, vomiting, hair loss, and immune system suppression.
Clinicians expect the Lovastatin-interferon combination will soon be used to treat pancreatic cancer, colon cancer, renal cancer, sarcoma, and mesothelioma, as well as other forms of asbestos cancer.
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